BioCentury

Current Editions

March 23, 2026
Where AI is integrating into the biotech venture funnel

Through proprietary and commercial AI tools, VCs aim to accelerate landscape mapping, deal flow and diligence. Will outcomes change?

Finance

Arrowhead’s bid to become a large-cap biotech

After 20 years of platform building and resets, Redemplo, cardiometabolic breadth and extrahepatic delivery could drive biotech’s next growth phase

Product Development

For Korea, risky innovation is the safest option — a Perspective

In the shadow of China, Korea biotech is building a brand around bold science and a broad technology base

Editor's Commentary

Ultra-rare disease community holds mock funeral at FDA

Parents are pressing for accelerated approvals of MPS treatments

Politics, Policy & Law

Asia’s innovation moment expands beyond China

An analysis of dealmaking in 2024-25 shows Asia biotechs, ex-China, leaning into enabling technologies and first-in-class bets

Deals

Product Development

Two cholesterol‑clearing drugs could fill different Niemann-Pick niches

Age at onset and delivery route may shape where cyclodextrin therapies fit in NPC

Recursion’s Khan: AI will be judged by the medicines it makes

AI’s clearest near-term gains, and its next frontier in drug development: The BioCentury Show

Emerging Company Profile

R1: China-to-U.S. NewCo planning global testing of new CKD mechanism

Via deal with China-based Alebund, the well-funded start-up is developing a therapy that could challenge phosphate binders in hyperphosphatemia

Excalipoint: Bringing co-stimulation, masking and more to solid tumor T cell engagers

With three T cell engager platforms and a trispecific in the clinic, the Shanghai-based biotech raises $68.7M in seed funding

Data Byte

44-week data bolster best-in-class case for Structure’s obesity pill

Oral GLP-1R agonist aleniglipron delivers up to 16.3% placebo-adjusted weight loss and will advance to Phase III

Discovery & Translation

Science Spotlight: Moving KRAS inhibitors upstream to high-risk patients

Plus: engineered receptors to target low-CD70 solid tumors, Xaira’s virtual cell model, and infectious disease company innovations

Regulation

Icotyde may provide clearest test yet of demand for oral psoriasis drugs

The newly approved pill from Protagonist and J&J narrows the efficacy gap with injectables

Politics, Policy & Law

In an eventful year, Makary hasn’t faced Congressional scrutiny

With support from Republican committee chairs, the FDA commissioner has side-stepped Congress

Congress revives SBIR funding, creates new large award

After months-long lapse, critical early-stage funding program reauthorized

Deals

Synnovation shareholders reap windfall from $2B sale of PI3Kα program to Novartis

Deal for mutation-selective molecule comes more than a year after Lilly’s purchase of Scorpion for breast cancer asset in same class

Finance

Misfolding company Congruence returns to the well for $39.5M round: Venture Report

Plus: Crossbow lines up its first shot in the clinic, and new rounds for Mestag, Unnatural Products, R1 and Excalipoint

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201