Autophagy enhancers as metabolic syndrome therapy

In a study published in Nature Communications, a team of South Korean researchers identified small molecule autophagy enhancers that could help treat metabolic syndromes.

Autophagy -- a lysomome-mediated degradation pathway -- is an increasingly popular target for drug developers looking to treat multiple diseases due to its role as a regulator of cellular homeostasis. While autophagy inhibition has shown promise in treating cancer, boosting autophagy could be a general strategy for combating neurodegenerative diseases involving aggregated proteins (see BioCentury Innovations, May 4, 2017)...