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ADC evolution: Horizon-Scanning Analysis
💡BioCentury maps the evolving antibody-drug conjugate (ADC) landscape across linker technologies, dual-payload strategies, and degrader-conjugate platforms, spotlighting site-specific conjugation methods that promise more homogeneous ADCs, dual-payload designs entering the clinic to counter resistance and tumor heterogeneity, and degrader-antibody conjugates (DACs) moving past early setbacks with renewed industry interest.
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