Thursday, April 25, 2013
Researchers at Harvard Medical School and Massachusetts General Hospital have shown that their previously described platform for
creating transplantable bioengineered organs from decellularized matrices can
be used to create a functional kidney.1 The researchers are refining
the process to improve kidney functionality and hope to begin large-animal
testing within five years.
Lou, K.-J. SciBX 6(16); doi:10.1038/scibx.2013.382
Published online April 25, 2013
Song, J.J. et al. Nat. Med.; published online April 14, 2013;
Contact: Harald C. Ott, Massachusetts General Hospital, Boston, Mass.
2. Badylak, S.F. Biomaterials
28, 3587-3593 (2007)
3. Ott, H.C. et al.
Nat. Med. 14, 213-221 (2008)
4. Ott, H.C. et al.
Nat. Med. 16, 927-933 (2010)
5. Lou, K.-J. SciBX
6. Soto-Gutierrez, A. et
al. Tissue Eng. Part C Methods 17, 677-686 (2011)
7. Uygun, B.E. et al.
Nat. Med. 16, 814-820 (2010)
AND INSTITUTIONS MENTIONED
Harvard Medical School, Boston, Mass.
Massachusetts General Hospital, Boston, Mass.
McGowan Institute for Regenerative Medicine, Pittsburgh, Pa.
Miromatrix Inc., Minneapolis, Minn.
Tengion Inc. (OTCQB:TNGN), Winston-Salem, N.C.
University of Minnesota, Minneapolis, Minn.
University of Pittsburgh, Pittsburgh, Pa.
University of Pittsburgh Medical Center, Pittsburgh, Pa.