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FDA approves J&J's siltuximab

April 24, 2014 12:33 AM UTC

FDA approved a BLA for Sylvant siltuximab from Johnson & Johnson (NYSE:JNJ) to treat multicentric Castleman's disease in patients who are HIV-negative and human herpes virus 8 (HHV-8)-negative. The chimeric mAb against IL-6 is the first approved treatment in the U.S. for the disease, a rare blood disorder that affects more than one group of lymph nodes in different anatomical areas. ...