Slow and inconsistent reimbursement practices coupled with a lack of data on health or economic outcomes at launch often slows uptake of new, high-priced molecular diagnostics and sequencing-based tests.
A first-of-its kind deal between Illumina Inc. and Harvard Pilgrim Health Care Inc. is intended to generate data to support broad reimbursement by multiple payers for non-invasive prenatal tests made by multiple testing companies.
Illumina’s stake in the non-invasive prenatal test (NIPT) market extends beyond its own Verifi genomic sequencing kits, which detect chromosomal abnormalities. That’s because many other NIPTs run on Illumina’s next-generation sequencing (NGS) platforms including the MiSeqDx and NextSeq 550Dx.
Illumina derives the bulk of its revenues from its sequencing instruments and assays and reagents that are purchased to use on the platforms. For 2017, the biotech reported $2.8 billion in revenue, with $1.8 billion (64%) from consumables and $515 million (19%) from instruments.
The company believes use of NGS tests in all pregnant women, not just those whose pregnancies are considered high risk, could reduce costs and improve outcomes for both mothers and babies.
But absent evidence to support those or other benefits