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Alnylam gets first RNAi drug approval

Twenty years after the scientific co-founders of Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY) discovered RNAi, a drug using the modality has been approved. On Aug. 10, FDA approved Onpattro patisiran to treat polyneuropathy caused by hereditary transthyretin (TTR)-mediated amyloidosis (hATTR) in adults. The indication is narrower than what Alnylam originally sought -- general treatment of hATTR -- in its NDA for Onpattro,

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