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Feb 27, 2012
 |  BC Week In Review  |  Clinical News  |  Preclinical Results

Pfizer preclinical data

Researchers at the University of California, San Francisco, Pfizer and Exelixis Inc. (NASDAQ:EXEL, South San Francisco, Calif.) reported data from mouse models of pancreatic cancer showing that simultaneous inhibition of c-Met and VEGF signaling reduced tumor invasiveness and metastasis, whereas inhibiting VEGF signaling alone increased invasion and metastasis of tumors. Specifically, mice...

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