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Mar 26, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Status

JX-594: Phase I/IIa started

Molecular target: Granulocyte macrophage colony-stimulating factor (GM-CSF) (CSF2)

Description: Recombinant vaccinia virus (addition of granulocyte macrophage colony-stimulating factor (GM-CSF) and deletion of thymidine kinase)

Indication: Treat metastatic colorectal cancer (mCRC)

Endpoint: Maximum tolerated dose (MTD), safety and response rate as measured by RECIST...

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