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12:53 PM
Sep 22, 2017
 |  BC Week In Review  |  Clinical News  |  Clinical Results

GSK's Trelegy Ellipta meets in Phase III IMPACT trial for COPD

GlaxoSmithKline plc (LSE:GSK; NYSE:GSK) and Innoviva Inc. (NASDAQ:INVA) reported data from the Phase III IMPACT trial in 10,355 chronic obstructive pulmonary disease (COPD) patients showing that once-daily Trelegy Ellipta fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) met the primary endpoint of reducing the annual rate of on-treatment moderate and severe exacerbations compared to both fluticasone furoate/vilanterol (0.91 vs. 1.07 exacerbations per year, p<0.001) and umeclidinium bromide/vilanterol (0.91 vs. 1.21 exacerbations per year, p<0.001). The double-blind, international trial enrolled patients with moderate to very severe symptomatic COPD and a history of...

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