12:00 AM
Feb 18, 2013
 |  BC Week In Review  |  Clinical News  |  Clinical Results

AVP-786: Phase I data

Data from 36 healthy volunteers in the first stage of a double-blind, crossover Phase I trial showed that AVP-786 plus low-dose quinidine had a comparable pharmacokinetic, safety and tolerability profile to that of AVP-923, a combination product containing dextromethorphan and a higher dose of quinidine (10 mg) than that given with AVP-786. Avanir said AVP-786 and AVP-923 contained the same amount of dextromethorphan in the trial, but declined to disclose the actual dose. The second stage of the trial, which has...

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