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Dec 03, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Tirasemtiv: Phase IIa data

The double-blind, crossover, U.S. Phase IIa CY 4023 trial in 32 patients with generalized myasthenia gravis showed that single doses of 250 and 500 mg oral tirasemtiv significantly and dose-dependently improved QMG scores vs. placebo at 6 hours post-treatment (0.49-point reduction per 250 mg; p=0.02 for the trend compared to placebo). Cytokinetics said it has not yet reported data comparing each individual dose of tirasemtiv to placebo. According to the...

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