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Oct 22, 2012
 |  BC Week In Review  |  Clinical News  |  Clinical Results

Soliris eculizumab: Phase II data

An investigator-initiated, single-arm, open-label, U.S. Phase II trial in 14 women with severe, relapsing neuromyelitis optica showed that Soliris significantly reduced the median annualized attack rate, the primary endpoint, from 3 attacks/patient pre-treatment to 0 attacks/patient after 12 months of treatment (p<0.0001). At 12 months, 12 patients were completely attack-free, while the other 2 patients had single possible relapses as reported by investigators - 1 patient had back pain without clinical or radiological evidence of inflammation of the spinal cord, while the other patient had new onset of visual blurring with...

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