BioCentury
ARTICLE | Clinical News

CT-1501R data

May 9, 1994 7:00 AM UTC

The Seattle company presented animal data on three different indications for lisofylline (CT-1501R), an inhibitor of the Bursten pathway, an intracellular, second messenger pathway that is activated in response to cell damaging stimuli.

CT-1501R prevented lung damage after loss of 30 percent blood volume in mice, reducing lung edema by 78 percent, lung bleeding by 83 percent, and infiltration of neutrophils into the organ by 31 percent. ...