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New target for Oncoceutics' GPCR-targeting compounds

Oncoceutics' compounds increase mitochondrial protease activity to kill cancer

Two academic teams have discovered Oncoceutics’ GPCR-targeting products kill cancer via an alternative mechanism: triggering apoptosis by activating a mitochondrial protease.

Oncoceutics Inc. is developing a pipeline of imipridones to antagonize or agonize GPCRs including dopamine receptors. Oncoceutics’ management team told BioCentury its lead product,

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