ARTICLE | Translation in Brief
Oncogenic gene fusions can create neoantigens
How gene fusions could be targets for immunotherapy
April 22, 2019 10:22 PM UTC
Memorial Sloan Kettering Cancer Center researchers have identified gene fusions as a source of cancer neoantigens that could be targeted by immunotherapy.
As companies develop immunotherapies against neoantigens, research is increasingly looking beyond point mutations for sources of the tumor-specific peptides that the immune system regards as non-self (see "Alt-Neoantigens")...
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