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The self-destructing pancreas

How pancreatic β cells may contribute to their own demise in Type I diabetes

A pair of independent papers from researchers from Washington University School of Medicine in St. Louis and Institut National de la Santé et de la Recherche Médicale (INSERM) illustrate how pancreatic β cells may contribute to their own destruction in Type I diabetes through the production of abnormal peptides, which then trigger an autoimmune T cell attack. The findings suggest therapies inhibiting the T cell response against these peptides,

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