Fungi fill the void

Can fungi substitute for bacteria in the microbiome?

In a Cell Host & Microbe study published last month, a team at Cincinnati Children’s Hospital Medical Center showed that replacing commensal bacteria with fungi reduced intestinal injury and prevented fatal lung infection in mice, underscoring the potential for harnessing non-bacterial components of the microbiome to treat disease.

Microbiome analyses have focused on bacteria primarily because of the dominant number of bacterial cells and technical

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