Blanketly blocking MLL

Boosting wild-type MLL to stop the translocated version from causing cancer

Seven years after it discovered the unifying factor underlying the 70 seemingly unrelated translocations that all lead to mixed-lineage leukemia (MLL), a Northwestern team has devised a therapeutic strategy that could work across virtually all versions of the disease.

In 2010, a group led by Ali Shilatifard discovered that the vast majority of loci into which the MLL gene

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