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ARTICLE | Emerging Company Profile

Scipher: decoding drug response from protein interactions

Scipher aims to improve drug response predictions by incorporating protein interaction networks in its gene expression analysis algorithms

June 6, 2019 9:02 PM UTC

To improve the accuracy of therapeutic response predictions, Scipher has incorporated protein-protein interaction maps into its machine learning-based analyses of patient gene expression data to spotlight pathologically relevant markers.

According to Scipher Medicine Corp. CEO Alif Saleh, 90% of patients prescribed the world's 10 top-selling drugs do not respond to therapy. The company ascribed the lack of efficacy to the irrelevance of the drug target in non-responding patients...