Bugs on film
How Scioto is using biofilm formulation to boost colonization of gut probiotics
Microbiome company Scioto Biosciences Inc. is turning a longstanding enemy of antibiotics developers -- biofilms -- into a delivery vehicle for probiotics.
The company expects its lead candidate SB-121, an orally delivered biofilm formulation of Lactobacillus reuteri, to be useful across a swath of diseases where patients are at risk of developing intestinal inflammation and leakage. Its lead indication is necrotizing enterocolitis, a rare and sometimes