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Aelin is synthesizing antimicrobial peptides to induce protein aggregation in Gram-negative bacteria

Aelin Therapeutics N.V. is developing first-in-class synthetic peptides that could treat antibiotic-resistant Gram-negative infections by inducing toxic protein aggregation within bacterial cells.

By harnessing a novel mechanism of action that disrupts proteostasis, Aelin could circumvent growing resistance to existing antibiotics, which typically act by disrupting the bacterial cell membrane.

Last year, scientific co-founders Joost Schymkowitz and Frederic Rousseau spun Aelin out

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