BioCentury
ARTICLE | Distillery Therapeutics

Melding bispecifics and CAR T cells to treat glioblastoma

August 15, 2019 9:38 PM UTC

An anti-EGFRvIII CAR T cell engineered to secrete an anti-CD3, anti-EGFR bispecific antibody could treat glioblastoma. In a mouse model of EGFRvIII-positive or EGFRvIII-negative glioblastoma, the engi...