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Therapeutics: P. falciparum dihydroorotate dehydrogenase (PfDHODH); P. vivax dihydroorotate dehydrogenase (PvDHODH)

Infectious disease

INDICATION: Malaria

In vitro and mouse studies identified triazolopyrimidine-based inhibitors of PfDHODH and PvDHODH that

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