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May 12, 2016
 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Peripheral benzodiazepine receptor (TSPO; PBR); Mdm2 p53 binding protein homolog (MDM2; HDM2)

Cancer

INDICATION: Brain cancer

In vitro studies identified an inhibitor of MDM2/p53 binding and TSPO that could help treat glioblastoma. Chemical synthesis and in vitro testing of 2-phenylindolylglyoxylyl dipeptides identified a compound that bound...

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