ARTICLE | Distillery Therapeutics
Therapeutics: DNA-directed DNA polymerase θ (POLQ); poly(ADP-ribose) polymerase (PARP)
February 26, 2015 8:00 AM UTC
Cell culture and mouse studies suggest inhibiting POLQ could help treat cancers deficient in homologous recombination (HR) or homology-directed DNA repair. In a human breast cancer cell line with comp...