1:12 PM
 | 
Mar 07, 2018
 |  BC Innovations  |  Distillery Techniques

Drug platforms

TECHNOLOGY: Engineered viruses

A method for enhancing viral sensitivity to host IFN could be used to generate highly immunogenic, live virus-based vaccines against infection. The approach involves using saturation mutagenesis and next-generation sequencing to compare genomes of the IFN-treated and untreated virus and identify mutations that enhance viral IFN sensitivity, then engineering the mutations into the wild-type virus to generate a hyper-IFN-sensitive...

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