1:12 PM
Mar 07, 2018
 |  BC Innovations  |  Distillery Techniques

Drug platforms

TECHNOLOGY: Engineered viruses

A method for enhancing viral sensitivity to host IFN could be used to generate highly immunogenic, live virus-based vaccines against infection. The approach involves using saturation mutagenesis and next-generation sequencing to compare genomes of the IFN-treated and untreated virus and identify mutations that enhance viral IFN sensitivity, then engineering the mutations into the wild-type virus to generate a hyper-IFN-sensitive...

Read the full 283 word article

User Sign in

Trial Subscription

Get a 4-week free trial subscription to BioCentury Innovations

Article Purchase

$35 USD