ARTICLE | Cover Story
Pinpointing Triggers in MS
February 28, 2008 8:00 AM UTC
Two recent papers identify key players in the early stages of multiple sclerosis, opening up a large class of potential therapeutic targets.
A new mouse model described in Nature Medicine has helped researchers uncover the identity of the immune cells responsible for brain inflammation, pointing to Th17 helper T cells as a leading suspect in triggering MS.1 The findings bolster ZymoGenetics Inc.'s rationale for pursuing its soluble interleukin-17 receptor in MS...