3:25 PM
 | 
Feb 13, 2019
 |  BC Extra  |  Preclinical News

Modifying adult human cells to produce insulin in situ

A University of Geneva team has expanded the strategies for replenishing insulin-producing cells in Type I diabetics by reprogramming human non-insulin-producing pancreatic islet cells, such as α cells, to adopt β cell properties. Pancreatic islet α cells secrete glucagon, while β cells secrete insulin.

Other options include transplantation of insulin-producing cells derived from differentiated stem cell-derived β cells, pancreatic progenitor cells, xenotransplants and expanded donor β cells (see

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