3:36 PM
May 08, 2018
 |  BC Extra  |  Preclinical News

SNS nerve loss drives hematopoietic stem cell aging

A paper published in Nature Medicine showed that the loss of sympathetic nervous system (SNS)nerves in bone marrow is a driver of hematopoietic stem cell (HSC) aging, suggesting that agonizing the receptors targeted by SNS-delivered neurotransmitters can “rejuvenate” HSCs during aging.

HSCs, which reside in a microenvironment in the bone marrow, lose their capacity to regenerate and differentiate into multiple lineages as they...

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