Patient-derived GI cancer organoids predict treatment response

Researchers at The Institute of Cancer Research have developed a living biobank of metastatic gastrointestinal cancer patient-derived organoids (PDOs), and showed PDOs could help predict patient responses to cancer treatment.

In a paper published in Science, the researchers wrote that while PDOs are increasingly used as preclinical models of cancer, there is little data on the capacity of PDOs to predict treatment responses in the clinic...