6:02 AM
Dec 11, 2017
 |  BC Extra  |  Preclinical News

Histone modifier is implicated in epithelial-mesenchymal transition

In a paper published in the Journal of Cell Biology, researchers at the Genentech Inc. unit of Roche (SIX:ROG; OTCQX:RHHBY) identified a histone modifier that may regulate epithelial-mesenchymal transition (EMT), a process associated with tumor cell invasiveness and chemotherapy resistance.

The Genentech team, led by VP of Cancer Immunology Ira Mellman, sought to identify epigenetic regulators of...

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