C4, Calico partner to treat aging-related diseases

Protein degradation company C4 Therapeutics Inc. (Cambridge, Mass.) and longevity company Calico LLC (South San Francisco, Calif.) partnered to develop therapies for diseases related to aging, including cancer.

Under the five-year deal, the partners will conduct preclinical research to discover small molecule protein degraders with therapeutic potential. Calico will be responsible for the programs' clinical development and commercialization. C4 declined to discuss financial terms, targets or indications involved in the deal...