Lisofylline phosphatidic acid data

The Seattle company reported efficacy of the compound, which inhibits PA, a mediator of oxidative damage. Cell Therapeutics also said it can predict patients at risk for ARDS.

As presented at the meeting of the American Society for Biochemistry and Molecular Biology in Keystone, Colo., researchers measured the ratio of free fatty acids (FFA), chemical by-products of PA metabolism, found in the blood. They found that the increase in the FFA ratio predicted which patients would develop the syndrome, and that the predictive value correlated with the severity of illness. ...