University of Massachusetts Medical School, et. al. other research news

University researchers published mousedata showing long-term survival of islet cell grafts in recipients mismatched at major and minor histocompatibility loci.

As reported in the Proceedings of the National Academy of Sciences, antibody to CD40L by itself allowed indefinite survival of the grafts in 40 percent of 25 recipients and delayed rejection in the rest. Adding small lymphocytes from the graft donors, depleted of T cells, led to long term survival in almost all recipients (22 of 23 mice; the one failure occurred at 118 days). ...