BioCentury
ARTICLE | Clinical News

Gilead preclinical data

December 4, 1995 8:00 AM UTC

GILD published animal data showing that Protein C Activator acted as an effective anticoagulant without any adverse impact on normal bleeding times in vivo.

As published in Nature, PCA provided dose-dependent, reversible anti-coagulation in primates without increasing baseline bleeding times, and without procoagulant activity. The compound is a modified version of thrombin. ...