Genoscope, The Institute for Genomic Research, University of Washington other research news
TIGR researchers published in Nature Genetics their estimate that the human genome contains 120,000 protein-coding genes. The estimate was based on an analysis of existing consensus expressed sequence tag (EST) sequences.
However, Washington researchers published in the same issue of Nature Genetics a separate estimate, based on a comparison of EST contigs with the sequence of human chromosome 22 or a non-redundant set of mRNAs, predicting that the human genome contains around 35,000 protein-coding genes. Also, Genoscope researchers published in that issue of Nature Genetics an estimate of 28,000-34,000 protein-coding genes based on homology comparisons between the pufferfish genome and either the draft sequence of the human genome or the Unigene set of human cDNAs. ...