Neurocrine preclinical data

FDA researchers and colleagues published in Nature Medicine the ability of an IL-4 fusion toxin to produce complete responses in mice with subcutaneous KS tumors. The researchers suggested that the fusion toxin, a combination of interleukin-4 and Pseudomonas exotoxin that binds to IL-4 receptors on cancer cells, could be therapeutically useful in AIDS-related KS. ...