Epivir 3TC nucleoside reverse transcriptase inhibitor: Marketed

Partner Glaxo Wellcome's Combivir, which combines BCHE's Epivir 3TC with Glaxo's Retrovir AZT in a single tablet, reduced viral load when given within 90 days of HIV infection in combination with Merck's Crixivan indinavir protease inhibitor. Of 71 consecutively enrolled HIV-infected patients, 20 were treated immediately upon diagnosis. After 12 weeks, 19 of the 20 had <500 HIV RNA copies/mL, and by week 32, all patients on the combination therapy had <20 copies/mL. ...