BioCentury
ARTICLE | Emerging Company Profile

Protuoso Bio: Building mix-and-match multi-functional biologics

The hub-and-spoke-structured company combines diverse protein modalities into single molecules for synergistic effects in complex diseases

August 15, 2026 1:11 AM UTC

Protuoso Biosciences is using synthetic biology engineering, computational protein design, and AI-based screening to build modular biologics that target multi-pathway diseases in a synergistic and scalable format.

“Think about incorporating antibodies with cytokines and peptides and other signaling molecules,” Protruso Inc. co-founder and COO Willie Xiang told BioCentury. ...