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ARTICLE | Deals

Jazz expands neuro reach with rare epilepsy takeout: Deals Report

Jazz to obtain KCNT1+ epilepsy program via $1.3B acquisition of Actio; plus Tarsus’ $800M takeout of Alkeus for Stargardt candidate; and more

August 10, 2026 11:24 PM UTC

Jazz’s deal to acquire venture-backed Actio adds a rare epilepsy treatment to the Irish pharma’s neurology portfolio, building on the company’s expertise in rare and severe forms of epilepsy.

The deal to buy Actio Biosciences Inc., announced Monday, gives Jazz Pharmaceuticals plc (NASDAQ:JAZZ) ABS-1230, an oral small molecule KCNT1 ion channel inhibitor in Phase I/II testing for KCNT1+ epilepsy, a rare genetic developmental and epileptic encephalopathy. Jazz will pay Actio $820 million up front, plus up to $500 million in approval and sales milestones...