Pinnacle: Designing oral peptides to close the gap with injectable biologics

Pinnacle is tackling oral peptides’ longstanding bioavailability problem with a design-first platform and a team that has done it before.

Historically, development of oral peptides has been hampered by enzyme degradation and poor gut permeability, resulting in low bioavailability and limited clinical success. Recent breakthroughs in formulation and design have produced multiple late-stage or approved oral peptide drugs, validating the modality...