DATA GRAPHICS | Data Byte
Recent megadeals reset the high end of private biotech M&A
Two biggest upfront payments for venture-backed biotech takeouts came this month; Kelonia’s was 65x the capital it raised
April 21, 2026 10:23 PM UTC
Headlined by this week’s Lilly takeout of Kelonia, a handful of recent deals suggests the ceiling for private biotech M&A may be moving higher, as pharmas compete for clinical assets in favored modalities and therapeutic areas.
In an analysis of private company takeouts since the start of 2021, BioCentury identified 20 $1 billion-plus deals for venture-backed, pure-play biotechs in which both the M&A upfront and the target company’s total venture capital raised were disclosed...