Atlas insights: Single-cell data point to druggable nodes in Down syndrome

Single‑cell atlases of human brains with Down syndrome may turn long-suspected pathological mechanisms into discrete, druggable nodes.

BioCentury’s weekly literature scans of 27 journals frequently identifies papers that function as disease “atlases” — observational patient studies, typically involving large-scale molecular profiling, that seek to capture the underlying biology and heterogeneity of disease. ...