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ARTICLE | Emerging Company Profile

Elkedonia: Antidepressants that act downstream of neurotransmitters

Seed-funded French start-up aiming at ELK1 to reboot neuroplasticity in depression

December 16, 2025 3:28 AM UTC

Argobio-founded Elkedonia is investigating a first-in-class intracellular target to treat neuropsychiatric disorders, starting with treatment-resistant depression.

The company’s approach is rooted in translational neuroscience research led by Jocelyne Caboche, director of research at the National Center for Scientific Research (CNRS) at Sorbonne University. ...