BioCentury
ARTICLE | Product Development

A trio of CAR T updates: Clinical Report 

Caribou reports allogeneic data in two cancer indications as Kyverna readies to bring an autoimmune CAR T into Phase III 

November 5, 2025 1:30 AM UTC

In a week with only one stock-moving clinical development, Sarepta’s confirmatory trial miss in Duchenne muscular dystrophy, a trio of CAR T cell therapies made quiet progress in refractory populations. Two of these were in cancer indications and one in an autoimmune setting.

Caribou Biosciences Inc. (NASDAQ:CRBU) reported data from two Phase I trials, ANTLER and CaMMouflage, testing allogeneic CAR T therapies in patients with relapsed or refractory B cell non-Hodgkin lymphoma and multiple myeloma, respectively...