BioCentury
ARTICLE | Deals

Novo buys Akero for $4.7B in third and largest deal in key liver disease class

Danish pharma gets FGF21 program that showed reversal of fibrosis among MASH patients in Phase IIb study; deal follows Boston Pharma, 89bio takeouts

October 9, 2025 9:23 PM UTC

Novo’s first major deal under new CEO Maziar Mike Doustdar is its planned acquisition of Akero, giving it an FGF21 program for MASH that effectively replaces a failed pipeline candidate that would have complemented approved therapy Wegovy in the indication.

Novo Nordisk A/S (CSE:NOVO B; NYSE:NVO) said Thursday it would pay $4.7 billion up front to acquire Akero Therapeutics Inc. (NASDAQ:AKRO), giving the Danish biopharma FGF21 analog efruxifermin. The treatment is in Phase III testing to treat metabolic dysfunction-associated steatohepatitis (MASH), also known as non-alcoholic steatohepatitis (NASH)...