Science Spotlight: Obesity, GLP-1R influence immune checkpoints; and more

Separate papers have suggested that obesity and GLP-1R activity influence immunity, hinting that GLP-1R could be an avenue for preventing transplant rejection and treating cancer. 

In the first study, a team at the University of Milan showed that GLP-1R may act as an immune checkpoint on T cells to directly inhibit CD8⁺ T cell immune response. ...