BioCentury
ARTICLE | Deals

Roche to challenge Merck in IBD via $7.1B Telavant takeout

Deal is latest in the evolving TL1A space, with three clinical candidates shifting into larger pharmas’ hands this year

October 23, 2023 10:17 PM UTC

Roche’s $7.1 billion deal for Roivant’s Telavant subsidiary is the latest in the rapidly strengthening field of TL1A inhibitors for autoimmune disease, with clinical data in IBD driving pharmas’ interest in the class.

The takeout delivers a quick, high-multiple return on an investment by Roivant Sciences Ltd. (NASDAQ:ROIV), which set up Telavant to house rights in the U.S. and Japan to an asset in-licensed from Pfizer Inc. (NYSE:PFE) in a deal announced in early December 2022. By contributing $45 million and pledging to contribute to ongoing development, Roivant obtained a 75% stake in the venture, while Pfizer held 25%...