BioCentury
ARTICLE | Emerging Company Profile

Sling: advancing an oral alternative to Tepezza for thyroid eye

First company created by sole investor TPG cleared for Phase IIb trial of asset Astellas had studied in cancer

June 28, 2022 7:50 PM UTC

The outsized commercial performance of Tepezza inspired Sling’s founders to repurpose a cancer therapy from Astellas and form a start-up that will develop it as an oral alternative to that thyroid eye disease drug.

Launched this month, Sling Therapeutics Inc. is the first start-up created by TPG, which is the sole investor in the company’s $35 million series A round via its Rise Fund. The company is advancing IGF1R inhibitor linsitinib under a license from Astellas Pharma Inc. (Tokyo:4503); terms are undisclosed...